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HEMICHOLINIUM 3
Descriptors Found:
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DeCS
Descriptor
English
:
Hemicholinium 3
Descriptor
Spanish
:
Hemicolinio 3
Descriptor
Portuguese
:
Hemicolínio 3
Synonyms
English
:
Hemicholinium
Tree Number:
D02.092.877.435
D02.675.276.435
Definition
English
:
A potent inhibitor of the high affinity uptake system for
CHOLINE
. It has less effect on the low affinity uptake system. Since
choline
is one of the components of
ACETYLCHOLINE
, treatment with
hemicholinium
can deplete
acetylcholine
from cholinergic terminals.
Hemicholinium 3
is commonly used as a
research
tool in animal and in vitro experiments.
Pharmacological Action:
Neurotransmitter Uptake Inhibitors
Cholinergic Agents
History Note
English
:
72
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
6575
Unique Identifier:
D006426
Occurrence in VHL
:
Similar:
DeCS